Date: 15 November 2022, 19h
Place: Sala Pere and Joan Coromines, IEC
Organization: Societat Catalana de Biologia
Speaker: Arcadi Navarro, ICREA lecturer and Genetics Professor at Pompeu Fabra University. Director of the Pasqual Maragall Foundation.
Understanding the genetic architecture of all kinds of phenotypes, mainly complex diseases, has been one of the great biomedical research challenges of the 21st century. The importance of this challenge is such that it was one of the main arguments, more than twenty years ago, for sequencing the human genome, which has allowed many of the subsequent advances. For almost two decades, the main methods of studying the relationship between genomes and phenoms have focused on comparing large numbers of humans who exhibit differences in phenotypes of interest. In this discussion, we will go through the main results and argue the importance of an inclusive vision of biodiversity: extending the comparative method to other species, beyond humans, is a very promising complementary strategy that allows some limitations of current methods to be overcome.